Kane and Alli came close before the equaliser and Eric Dier's deflected drive struck the post in first-half stoppage time, making Ander Herrera's 62nd-minute victor and Spurs' subsequent lack of a late rally tough to take.
The last time Spurs won in an FA Cup semi-final was a 3-1 victory over Arsenal in 1991, going on to beat Nottingham Forest in the final.
Tottenham pushed for a way back into the match, but an equaliser remained elusive and it means the Lilywhites' wait for silverware will continue into an 11th year.
Alexis Sanchez has scored eight goals in his eight appearances at Wembley for club and country, including six goals in five FA Cup matches.
He said that Tottenham, who have been without a trophy since 2008, need more time to build the mentality needed to win trophies.
Jose Mourinho set for possible date with Chelsea: Mourinho has enjoyed a hot-cold relationship with the Blues fans since leaving Stamford Bridge and he would love to have another opportunity to beat the west London outfit.
And that, more than anything, characterised his performance: one full of heart, dedication, sheer will - and one that played a huge role in steering United to the FA Cup final.
Although Tottenham threatened at times and saw much of the ball, the midfield trio of Nemanja Matic, Pogba and Herrera managed to retain enough possession and broke up play to see United over the line, with Ander Herrea's brilliant strike sending the Red Devils to their 20th FA Cup final.
Pochettino has now suffered a League Cup final defeat and successive FA Cup semi-final losses with Tottenham.
United settled again and hit back midway through the half as Paul Pogba outmuscled Mousa Dembele on the left wing, picked out Sanchez with an inch-perfect cross which evaded the Spurs centre-backs, and the Chilean headed home across the stationary Michel Vorm.
It was the fifth straight FA Cup game at Wembley in which the Chile worldwide has scored, with the previous four coming for Arsenal.
"We knew we were going to fight sometimes and defend together". We were on top for periods of the game. It was unfair to go in 1-1 at half-time.
They weren't even playing at Old Trafford today.
While Mourinho has fallen short in the English Premier League behind newly crowned champion Manchester City, United is second and on course for its highest finish since Alex Ferguson retired in 2013.
Liverpool missed a chance to considerably stretch its advantage over Tottenham in one of Saturday's two league games.
The Red Devils are aiming to finish as runners-up to Manchester City in the table, and they are now second behind the newly-crowned champions.
The new details come after Eurasian regulatory filings this month suggest we're just weeks away from new iPhones being unveiled. On Friday there was a burst of negative sentiment about Apple that left their stock down 4 percent after the market closed.
While Sri Reddy has now apologised to Pawan but the man is no mood to spare anyone who abused his mother. The notice also warned to take appropriate legal procedure on Pawan Kalyan if he fails to comply.
And if you are an Airtel customer, on buying the Nokia 8 Sirocco you will be entitled to get an additional data benefit of 120GB. Nokia 7 Plus will be available at a recommended best price of Rs. 25,999 and comes in Black/Copper and White/Copper colours.
Tristan wants Khloe to forgive him and wants to assure her that they can have their fairytale family. True is a sweet name for Khloe's first born, but you better believe that Twitter had some reactions.
The charge came after Hawley earlier this week said his office found evidence that Greitens' use of the donor list broke the law. Eric Greitens has been charged with a felony related to his use of a charity donor list for his 2016 political campaign.
There were obviously some talented players opposite of Jones as well, but those were mostly back-ups and other young players. DB - Once again, Diggs enters an A-Day game as one of Alabama's starting cornerbacks. "Without me saying it ... two years".
The day before he died his team reached out with an urgent request for help to an opioid addiction specialist, according to CNN . The doctor sent his son, Andrew, to Minnesota that night, and the younger Kornfeld was among those who found Prince's body.
Any proposals or recommendations that this group would agree upon need to be later ratified by the full-line-up meeting in June. Although the official goal is to bring inventories back to normal levels, unofficially, the target is to prop up oil prices.
On the undercard Tommy Coyle stunned Sean Dodd to win the Commonwealth lightweight title. "I'm not a fighter to run away". Khan then pinned Lo Greco to the ropes before the super-welterweight contest ended moments after it had started.
Fellow passengers pulled the passenger - identified as Jennifer Riordan, 43 - back in, but she later died of her injuries. The engine explosion on Southwest Airlines flight 1380 on Tuesday was caused by a fan blade that broke off, the FAA said.
School walkouts were canceled districtwide in Marion County after the shooting, according to school board member Nancy Stacy. Mailhiot said about 15 people in the classroom waited over 30 minutes to be evacuated by Ocala police.
Coli outbreak warning in U.S. expands to all romaine lettuce
Nugget Markets, Safeway and Raley's told us the romaine lettuce they sell does not come from the Yuma, Arizona growing region. People usually get sick from Shiga toxin-producing E. coli (STEC) 2-8 days (average of 3-4 days) after swallowing the germ.
AT&T and Verizon have been working together to screw you
Observers of the trial say AT&T appears to have an advantage after exposing weaknesses in the government's pricing power claims. This is likely why CNBC believes that it was Apple who contacted the government to complain about the problem.
Kylie Jenner Just Shared The Cutest Videos Of Baby Stormi
Her black hair was shaped into a chic bob. "I hope theres a back seat for your attractive baby girl", another said. Kylie Jenner slammed for attending Coachella . 'Hi baby girl, ' she said, before adding: 'I love you, I love you'.
Cleveland 'lucky' to beat Pacers, James says after 100-97 win
Right out the gate, LeBron's first 16 points were the only points scored by the Cavaliers as they jumped out to an early lead. Oladipo will continue his high-level play, and the rest of the Pacers should follow suit. "Kyle was great for us", Lue said.
Queen officially begins handover process for Charles
Her Majesty avoids long-haul flights and it will be some time before the biennial summit returns to England. Prince Charles is said to have widespread backing to continue the Queen's role, including from Theresa May.